Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.83 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 5/20 | 0.57 |
| ▸ | MMP8 | P22894 | 5/20 | 0.57 |
| ▸ | MMP13 | P45452 | 5/20 | 0.57 |
| ▸ | MMP12 | P39900 | 4/20 | 0.57 |
| ▸ | MMP14 | P50281 | 4/20 | 0.57 |
| ▸ | MMP16 | P51512 | 4/20 | 0.57 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 4/20 | 0.53 |
| ▸ | MMP1 | P03956 | 2/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15423745 | 0.94 | PKM (0.73) | PKMGAAHTR6HTTSMN1; SMN2 | |
| SCHEMBL20129486 | 0.94 | PKM (0.73) | PKMGAAHTR6HTTSMN1; SMN2 | |
| SCHEMBL13074716 | 0.91 | PKM (1.00) | PKMGAAHTTMMP2MMP8 | |
| SCHEMBL14486413 | 0.91 | PKM (1.00) | PKMGAAHTTMMP2MMP8 | |
| SCHEMBL835692 | 0.91 | PKM (1.00) | PKMGAAHTTMMP2MMP8 | |
| SCHEMBL10672859 | 0.90 | HTT (0.73) | PKMGAAHTTSMN1; SMN2MMP2 | |
| SCHEMBL10172900 | 0.89 | PKM (0.66) | PKMGAAHTR6HTTSMN1; SMN2 | |
| SCHEMBL12091354 | 0.89 | PKM (0.66) | PKMGAAHTTSMN1; SMN2MMP2 | |
| SCHEMBL7545245 | 0.87 | PKM (0.61) | PKMGAAHTTSMN1; SMN2MMP2 | |
| SCHEMBL9704374 | 0.86 | PKM (0.61) | PKMGAAHTR6HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650330-B2 | Process for the synthesis of aryl sulfones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-16 | — | — | US | claimed |
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-10-20 | — | — | US | claimed |
| WO-2015087352-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-06-18 | — | — | WO | claimed |
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | claimed |
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | WYETH (US) | 2006-12-07 | — | — | US | claimed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | claimed |
| WO-2001083434-B1 | P-(SULFONYL)-ARYL AND HETEROARYLS AMINES | — | 2002-04-25 | — | — | WO | claimed |
| EP-3807090-B1 | METHOD FOR MANUFACTURING A THREE-DIMENSIONAL OBJECT USING A POLY(ARYL ETHER SULFONE) POLYMER AND A PER(HALO)FLUOROPOLYMER | SOLVAY SPECIALTY POLYMERS USA (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-3972840-B1 | ADDITIVE MANUFACTURING METHOD FOR MAKING A THREE-DIMENSIONAL OBJECT | SOLVAY SPECIALTY POLYMERS USA (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116496136-A | Diaryl sulfone compound and preparation method thereof | 华北水利水电大学 | 2023-07-28 | — | — | CN | disclosed |
| US-11685829-B2 | Process for preparing particles of aromatic polymers, particles obtainable by said process and their uses | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2023-06-27 | — | — | US | disclosed |
| US-11654615-B2 | Method for manufacturing a three-dimensional object | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2023-05-23 | — | — | US | disclosed |
| US-20230150930-A1 | PHOTOCURABLE POLYMER COMPOSITIONS | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2023-05-18 | — | — | US | disclosed |
| US-4957925-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS, TREATMENT OF ANGINA | SANOFI (FR) | 1990-09-18 | — | — | US | disclosed |
| US-4837301-A | FROM ALKALI MTEAL SULFIDES AND AROMATIC DIHALOGEN COMPOUNDS; IMPROVED CORROSION RESISTANCE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-06 | — | — | US | disclosed |
| EP-0302792-A2 | Alkylaminoalkoxyphenyl derivatives, process of preparation and compositions containing the same | SANOFI (FR) | 1989-02-08 | — | — | EP | disclosed |
| EP-0302793-A2 | Aralkylaminoalkoxyphenyl derivatives, process of preparation and compositions containing the same | ELF SANOFI (FR) | 1989-02-08 | — | — | EP | disclosed |
| EP-0275007-A2 | Process for the preparation of highly molecular, optionally branched polyarylene sulfides | BAYER AG (DE) | 1988-07-20 | — | — | EP | disclosed |
| EP-0083204-A2 | 2-Aminophenol derivatives and process for their preparation | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-07-06 | — | — | EP | disclosed |
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150930-A1 | PHOTOCURABLE POLYMER COMPOSITIONS | ALG3, HTR3D, LCP1 | PKM 1560/4885GAA 1970/4885HTR6 3015/4885 |
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | ARSA, TPST2, STS | PKM 2141/4885GAA 423/4885HTR6 1035/4885 |
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | SFRP1, SOS1, FZD7 | PKM 4493/4885GAA 4113/4885HTR6 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.