Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120129 | 0.93 | CCR2 (0.38) | CCR2KCNH2CCR1TMEM97SIGMAR1 | |
| SCHEMBL13074577 | 0.90 | CCR2 (0.35) | CCR2KCNH2CCR1TMEM97SIGMAR1 | |
| SCHEMBL1119970 | 0.86 | CCR2 (0.40) | CCR2KCNH2CCR1TMEM97SIGMAR1 | |
| SCHEMBL13011667 | 0.84 | CCR2 (0.39) | CCR2KCNH2CCR1TMEM97SIGMAR1 | |
| SCHEMBL1119842 | 0.84 | CCR2 (0.40) | CCR2KCNH2CCR1TMEM97SIGMAR1 | |
| SCHEMBL1120068 | 0.84 | CCR2 (0.39) | CCR2KCNH2CCR1TMEM97SIGMAR1 | |
| SCHEMBL13011668 | 0.84 | CCR2 (0.39) | CCR2KCNH2CCR1TMEM97SIGMAR1 | |
| SCHEMBL13011550 | 0.83 | CCR2 (0.38) | CCR2KCNH2CCR1TMEM97SIGMAR1 | |
| SCHEMBL1119813 | 0.83 | KCNH2 (0.42) | CCR2KCNH2CCR1TMEM97SIGMAR1 | |
| SCHEMBL13078618 | 0.83 | KCNJ1 (0.32) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129843-A1 | DIHYDRONAPHTHYRIDINYL AND RELATED COMPOUNDS FOR USE IN TREATING OPHTHALMOLOGICAL DISORDERS | CYTOPATHFINDER, INC. (JP) | 2010-11-11 | — | — | WO | disclosed |
| WO-2009076512-A1 | CARBOXAMIDΞ COMPOUNDS AND THEIR USE AS CHEMOKINE RECEPTOR AGONISTS | EPIX DELAWARE, INC. (US) | 2009-06-18 | — | — | WO | disclosed |