Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 4/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120129 | 0.91 | CCR2 (0.38) | — | |
| SCHEMBL13074817 | 0.83 | CCR2 (0.34) | SMN1; SMN2 | |
| SCHEMBL1119752 | 0.83 | CYP3A4 (0.35) | KCNJ1PLGALDH1A1SMN1; SMN2CTSC | |
| SCHEMBL1119970 | 0.82 | CCR2 (0.40) | — | |
| SCHEMBL15353817 | 0.81 | KCNJ1 (0.32) | KCNJ1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15353819 | 0.81 | KCNJ1 (0.32) | KCNJ1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15353818 | 0.81 | KCNJ1 (0.32) | KCNJ1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13011667 | 0.80 | CCR2 (0.39) | — | |
| SCHEMBL1120068 | 0.80 | CCR2 (0.39) | — | |
| SCHEMBL1119842 | 0.80 | CCR2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286136-A1 | DIHYDRONAPHTHYRIDINYL AND RELATED COMPOUNDS FOR USE IN TREATING OPHTHALMOLOGICAL DISORDERS | JONES SIMON | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286136-A1 | DIHYDRONAPHTHYRIDINYL AND RELATED COMPOUNDS FOR USE IN TREATING OPHTHALMOLOGICAL DISORDERS | ALDH1A2, QDPR, PDE6C | KCNJ1 1378/4885PLG 3141/4885ALDH1A1 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.