Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSH | P09668 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13358801 | 0.71 | USP2 (0.41) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL15802703 | 0.68 | MAPT (0.36) | — | |
| SCHEMBL14287526 | 0.68 | — | — | |
| SCHEMBL1525596 | 0.67 | — | — | |
| SCHEMBL14065524 | 0.67 | ALDH1A1 (0.43) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL10835748 | 0.65 | NPSR1 (0.31) | — | |
| SCHEMBL19259373 | 0.65 | USP2 (0.41) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL17805898 | 0.64 | TSHR (0.40) | ALDH1A1 | |
| SCHEMBL4428008 | 0.64 | USP2 (0.43) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL454299 | 0.63 | TSHR (0.43) | USP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825200-B2 | olefins functionalized with free radical initiators, copolymerization with ethylene and subsequent grafting with butyl acrylate; initiating monomer is from 5-norbornen-2-ol; 5-norbornen-2-yl 4-(1-(1-(2,2,6,6-tetramethylpiperidinoxy))ethyl)benzyl ether; nickel complex catalyst | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-11-02 | — | — | US | disclosed |
| US-20070149732-A1 | Controlled free radical grafting from polyolefins | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2007-06-28 | — | — | US | disclosed |