Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | CTSH | P09668 | 1/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.54 |
| ▸ | GLP1R | P43220 | 9/20 | 0.54 |
| ▸ | GCGR | P47871 | 8/20 | 0.54 |
| ▸ | GIPR | P48546 | 5/20 | 0.53 |
| ▸ | CALCA | P06881 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12589895 | 0.86 | CTSL (0.58) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL13038595 | 0.84 | CXCL8 (0.60) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL29697149 | 0.79 | CXCR4 (0.65) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL30658250 | 0.78 | GLP1R (0.69) | CTSLCTSSCTSKCTSHGLP1R | |
| SCHEMBL12557082 | 0.78 | CXCR4 (0.52) | CXCR4GLP1RGCGRGIPR | |
| SCHEMBL30883231 | 0.78 | CXCR4 (0.68) | CXCR4GLP1RCALCA | |
| SCHEMBL29742984 | 0.78 | CXCR4 (0.63) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL13881394 | 0.78 | CXCL8 (0.60) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL29867926 | 0.77 | CXCR4 (0.65) | CXCR4GLP1RGCGRCALCA | |
| SCHEMBL19448547 | 0.77 | CXCL8 (0.59) | CTSLCTSSCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129581-A1 | POLYMER MICELLES CONTAINING SN-38 FOR THE TREATMENT OF CANCER | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2010-11-11 | — | — | WO | disclosed |