Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CBL | P22681 | 1/20 | 0.39 |
| ▸ | CBLB | Q13191 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12333052 | 0.89 | GSK3A (0.42) | ALDH1A1KDM4ECYP1A2HPGDBLM | |
| SCHEMBL10059423 | 0.86 | ALDH1A1 (0.59) | ALDH1A1KDM4ECYP1A2HPGDBLM | |
| SCHEMBL10305669 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KDM4ECYP1A2HPGDBLM | |
| SCHEMBL10079103 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4ECYP1A2HPGDBLM | |
| SCHEMBL142716 | 0.84 | NPC1 (0.46) | ALDH1A1KDM4ECYP1A2HPGDBLM | |
| SCHEMBL10059409 | 0.82 | KDM4E (0.36) | ALDH1A1KDM4ECYP1A2HPGDBLM | |
| SCHEMBL10079418 | 0.82 | KDM4E (0.37) | ALDH1A1KDM4ECYP1A2HPGDBLM | |
| SCHEMBL6116854 | 0.82 | KIF11 (0.47) | ALDH1A1KDM4ECYP1A2HPGDBLM | |
| SCHEMBL142926 | 0.82 | KIF11 (0.47) | ALDH1A1KDM4ECYP1A2HPGDBLM | |
| SCHEMBL141047 | 0.82 | MIF (0.46) | ALDH1A1KDM4ECYP1A2HPGDBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135470-A1 | PIFENIDONE DERIVATIVES FOR TREATING BRONCHIAL ASTHMA | INTERMUNE, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010132864-A1 | METHODS OF TREATING HIV PATIENTS WITH ANTI-FIBROTICS | INTERMUNE, INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2009149188-A1 | COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY AND FIBROTIC DISORDERS | INTERMUNE, INC. (US) | 2009-12-10 | — | — | WO | disclosed |