Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 2/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253614 | 0.78 | L3MBTL1 (0.62) | L3MBTL1CREBBPPOLBTDP1HDAC3 | |
| SCHEMBL272966 | 0.78 | L3MBTL1 (0.62) | L3MBTL1CREBBPPOLBTDP1HDAC3 | |
| SCHEMBL1244019 | 0.76 | L3MBTL1 (0.61) | L3MBTL1CREBBPPOLBTDP1HDAC3 | |
| SCHEMBL6264956 | 0.76 | L3MBTL1 (0.65) | L3MBTL1CREBBPPOLBTDP1CYP19A1 | |
| SCHEMBL17298120 | 0.75 | L3MBTL1 (0.59) | L3MBTL1CREBBPPOLBTDP1HDAC3 | |
| SCHEMBL10283891 | 0.74 | L3MBTL1 (0.62) | L3MBTL1CREBBPPOLBTDP1HDAC3 | |
| SCHEMBL950986 | 0.74 | MAPT (0.67) | L3MBTL1CREBBPPOLBTDP1HDAC3 | |
| SCHEMBL130830 | 0.74 | L3MBTL1 (0.62) | L3MBTL1CREBBPPOLBTDP1CYP19A1 | |
| SCHEMBL2413457 | 0.74 | L3MBTL1 (0.62) | L3MBTL1CREBBPPOLBTDP1HDAC3 | |
| SCHEMBL14920616 | 0.74 | L3MBTL1 (0.62) | L3MBTL1CREBBPPOLBTDP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129567-A1 | PYRROLO [2, 3. B] PYRIDINES WHICH INHIBIT RAF PROTEIN KINASE | PLEXXIKON, INC. (US) | 2010-11-11 | — | — | WO | disclosed |