Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17988973 | 0.85 | CYP3A4 (0.41) | CYP3A4LMNAMAPTAPEX1MAPK1 | |
| SCHEMBL13076394 | 0.77 | KDM4E (0.36) | CYP3A4LMNAMAPTPMP22 | |
| SCHEMBL17989022 | 0.77 | PIK3CA (0.36) | CYP3A4MAPK1CYP2A6 | |
| SCHEMBL15868876 | 0.77 | HRH4 (0.44) | CYP3A4LMNAMAPTAPEX1MAPK1 | |
| SCHEMBL12959195 | 0.76 | POLB (0.31) | — | |
| SCHEMBL15868868 | 0.76 | HTR3A (0.41) | CYP3A4LMNAMAPT | |
| SCHEMBL16361365 | 0.75 | HCRTR1 (0.36) | MAPT | |
| SCHEMBL17989897 | 0.75 | KDM4E (0.46) | CYP3A4LMNAMAPTMAPK1 | |
| SCHEMBL13087071 | 0.74 | ALDH1A1 (0.39) | CYP3A4LMNAMAPTMAPK1 | |
| SCHEMBL10027638 | 0.73 | KDM4E (0.39) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126234-A1 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | DOW ADVANCED DISPLAY MATERIALS,LTD. (KR) | 2010-11-04 | — | — | WO | disclosed |