Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13075427 | 0.91 | KDM4E (0.57) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL12726049 | 0.90 | ALDH1A1 (0.57) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL15108020 | 0.88 | MAPT (0.52) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL15108024 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL15107971 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL12726196 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL13075440 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL12726189 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL13075824 | 0.84 | HRH3 (0.63) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL12726220 | 0.84 | ALDH1A1 (0.57) | KDM4EALDH1A1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486936-B2 | Antagonist of smoothened | AllaChem, LLC (US) | 2013-07-16 | — | — | US | disclosed |
| WO-2010129620-A1 | IMIDAZO [ 1, 2 -A] PYRIDIN-2 -YL-PHENYL DERIVATIVES TO BE USED IN CANCER TREATMENT | ALLA CHEM, LLC (US) | 2010-11-11 | — | — | WO | disclosed |