Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MOK | Q9UQ07 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12726255 | 0.93 | HRH3 (0.55) | HRH3KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL12726270 | 0.92 | HRH3 (0.54) | HRH3KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL13075438 | 0.88 | HRH3 (0.48) | HRH3KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL15107364 | 0.87 | KDM4E (0.58) | HRH3KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL13075440 | 0.84 | KDM4E (0.54) | HRH3KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL13075823 | 0.84 | KDM4E (0.56) | HRH3KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL12726189 | 0.84 | KDM4E (0.59) | HRH3KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL13075427 | 0.83 | KDM4E (0.57) | HRH3KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL12726052 | 0.83 | HRH3 (0.59) | HRH3KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL12726220 | 0.82 | ALDH1A1 (0.57) | HRH3KDM4EKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129620-A1 | IMIDAZO [ 1, 2 -A] PYRIDIN-2 -YL-PHENYL DERIVATIVES TO BE USED IN CANCER TREATMENT | ALLA CHEM, LLC (US) | 2010-11-11 | — | — | WO | disclosed |