Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 15/20 | 0.45 |
| ▸ | FABP3 | P05413 | 5/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076246 | 0.87 | NPC1 (0.37) | DYRK1ARAB9ASMN1; SMN2PTGES | |
| SCHEMBL3797909 | 0.86 | PTGES (0.51) | FABP4FABP3FABP5PTGES | |
| SCHEMBL13076235 | 0.77 | PTGES (0.49) | PTGES | |
| SCHEMBL3814333 | 0.76 | PTGES (0.40) | MAPTRAB9APTGES | |
| SCHEMBL3796320 | 0.76 | PTGES (0.49) | PTGES | |
| SCHEMBL3790651 | 0.75 | PTGES (0.51) | MAPTRAB9ASMN1; SMN2PTGES | |
| SCHEMBL13076230 | 0.74 | PTGES (0.43) | PTGES | |
| SCHEMBL3796002 | 0.74 | PTGES (0.43) | PTGES | |
| SCHEMBL3799806 | 0.73 | PTGES (0.44) | MAPTRAB9APTGES | |
| SCHEMBL29662800 | 0.73 | PTGES (0.43) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127152-A2 | COMPOUNDS AND COMPOSITIONS AS MICROSOMAL PROSTAGLANDIN E SYNTHASE-1 INHIBITORS | IRM LLC (BM) | 2010-11-04 | — | — | WO | disclosed |