Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17655755 | 0.76 | TPMT (0.62) | LMNATPMTKMT2ACA12CA1 | |
| SCHEMBL290542 | 0.73 | LMNA (0.69) | LMNATPMTKMT2AALDH1A1MAPT | |
| SCHEMBL19272078 | 0.72 | LMNA (0.53) | LMNATPMTKMT2ACA12CA1 | |
| Hydrochloric Acid SCHEMBL29142671 | 0.71 | LMNA (0.67) | LMNATPMTKMT2AALDH1A1MAPT | |
| Chloroform SCHEMBL7815652 | 0.71 | LMNA (0.60) | LMNATPMTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL4548527 | 0.70 | LMNA (0.40) | LMNATPMTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL31059012 | 0.69 | LMNA (0.58) | LMNATPMTALDH1A1SMN1; SMN2TUBB4A | |
| SCHEMBL7374627 | 0.69 | LMNA (0.58) | LMNATPMTALDH1A1SMN1; SMN2TUBB4A | |
| SCHEMBL17655663 | 0.69 | TPMT (0.70) | LMNATPMTKMT2ACA12CA1 | |
| SCHEMBL1928259 | 0.69 | LMNA (0.62) | LMNATPMTKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126719-A1 | NEUROPROTECTIVE COMPOUNDS AND THEIR USE | MCW RESEARCH FOUNDATION, INC. (US) | 2010-11-04 | — | — | WO | disclosed |