Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.53 |
| ▸ | TUBB | P07437 | 3/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TOP1 | P11387 | 3/20 | 0.49 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24106215 | 0.89 | LMNA (0.55) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL24106208 | 0.88 | LMNA (0.53) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL668055 | 0.86 | TSHR (0.64) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL290542 | 0.85 | LMNA (0.69) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL668245 | 0.85 | TUBB4A (0.50) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23467799 | 0.85 | TUBB1 (0.50) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL29142671 | 0.83 | LMNA (0.67) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3326825 | 0.82 | TUBB4A (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13775501 | 0.82 | ACHE (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15266000 | 0.82 | ALOX5 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814319-B9 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2025-01-01 | — | — | EP | disclosed |
| EP-3814319-B1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2024-08-14 | — | — | EP | disclosed |
| US-11970431-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-04-30 | — | — | US | disclosed |
| US-20210309600-A1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2021-10-07 | — | — | US | disclosed |
| US-20210309600-A1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2021-10-07 | — | — | US | disclosed |
| US-11046636-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-11046636-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| EP-3814319-A1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | Johnson & Johnson Vision Care, Inc. (US) | 2021-05-05 | — | — | EP | disclosed |
| CN-112334444-A | Polymerizable absorbers for UV and high energy visible light | 强生视力健公司 | 2021-02-05 | — | — | CN | disclosed |
| EP-1589007-B1 | 5-membered heterocycle derivatives, production thereof and their use as medicaments | IPSEN PHARMA (FR) | 2015-06-03 | — | — | EP | disclosed |
| US-7291641-B2 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2007-11-06 | — | — | US | disclosed |
| US-20070179153-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S) | 2007-08-02 | — | — | US | disclosed |
| US-20070179153-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S) | 2007-08-02 | — | — | US | disclosed |
| US-20070179153-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S) | 2007-08-02 | — | — | US | disclosed |
| US-20070054900-A1 | 4-Phenlthiazole and 4-phenylimidizole derivatives and their use as medicaments for the treatment of neurodegenerative diseases, pain and epilepsy | SOCIETE DE CONSEILS DE RECHERCHES ET (FR) | 2007-03-08 | — | — | US | disclosed |
| US-20070021390-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | SCRAS | 2007-01-25 | — | — | US | disclosed |
| US-20070021390-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | SCRAS | 2007-01-25 | — | — | US | disclosed |
| US-20070021390-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | SCRAS | 2007-01-25 | — | — | US | disclosed |
| US-20050038087-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | IPSEN PHARMA S.A.S. (FR) | 2005-02-17 | — | — | US | disclosed |
| US-20040132788-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021390-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | PARK7, SNCA, COMT | LMNA 2727/4885TUBB4A 181/4885TUBB 152/4885 |
| US-20070179153-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | PARK7, SNCA, SDHA | LMNA 2628/4885TUBB4A 85/4885TUBB 63/4885 |
| US-20050038087-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | OXER1, OPRL1, OPRK1 | LMNA 4096/4885TUBB4A 1442/4885TUBB 1032/4885 |
| US-20040132788-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | OPRK1, HCN1, P2RX7 | LMNA 3964/4885TUBB4A 717/4885TUBB 837/4885 |
| US-11970431-B2 | Polymerizable absorbers of UV and high energy visible light | F12, RAD54L, RAD51 | LMNA 1318/4885TUBB4A 3304/4885TUBB 4004/4885 |
| US-11046636-B2 | Polymerizable absorbers of UV and high energy visible light | F12, IK, RAD51 | LMNA 1117/4885TUBB4A 3585/4885TUBB 4092/4885 |
| US-20070054900-A1 | 4-Phenlthiazole and 4-phenylimidizole derivatives and their use as medicaments for the treatment of neurodegenerative diseases, pain and epilepsy | TPMT, P2RX4, CACNA1I | LMNA 3612/4885TUBB4A 453/4885TUBB 1072/4885 |
| US-20210309600-A1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | F12, RAD54L, RAD51 | LMNA 1318/4885TUBB4A 3304/4885TUBB 4004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.