Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.73 |
| ▸ | TP53 | P04637 | 8/20 | 0.73 |
| ▸ | MAPT | P10636 | 8/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.73 |
| ▸ | RECQL | P46063 | 3/20 | 0.73 |
| ▸ | CDK2 | P24941 | 2/20 | 0.73 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144730 | 0.86 | MEN1 (0.74) | MEN1KMT2AKDM4ECYP3A4TP53 | |
| SCHEMBL23791700 | 0.86 | MEN1 (0.59) | MEN1KMT2AKDM4ECYP3A4TP53 | |
| SCHEMBL29437764 | 0.85 | MEN1 (1.00) | MEN1KMT2AKDM4ECYP3A4TP53 | |
| SCHEMBL15676575 | 0.85 | MEN1 (1.00) | MEN1KMT2AKDM4ECYP3A4TP53 | |
| SCHEMBL169366 | 0.85 | MEN1 (1.00) | MEN1KMT2AKDM4ECYP3A4TP53 | |
| SCHEMBL30626973 | 0.85 | MEN1 (1.00) | MEN1KMT2AKDM4ECYP3A4TP53 | |
| SCHEMBL27451564 | 0.83 | MEN1 (0.97) | MEN1KMT2AKDM4ECYP3A4TP53 | |
| SCHEMBL3066182 | 0.82 | MEN1 (0.78) | MEN1KMT2AKDM4ECYP3A4TP53 | |
| SCHEMBL2746872 | 0.81 | MEN1 (0.90) | MEN1KMT2AKDM4ECYP3A4TP53 | |
| SCHEMBL14690781 | 0.81 | MEN1 (0.77) | MEN1KMT2AKDM4ECYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129138-A2 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | LIMERICK BIOPHARMA (US) | 2010-11-11 | — | — | WO | disclosed |