Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 11/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 11/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 1.00 |
| ▸ | TP53 | P04637 | 10/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 1.00 |
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 7/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 7/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 6/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 6/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 4/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 4/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 1.00 |
| ▸ | CDK2 | P24941 | 3/20 | 1.00 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | HPGD | P15428 | 7/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30626973 | 1.00 | MEN1 (1.00) | MEN1KMT2ACYP3A4KDM4ETP53 | |
| SCHEMBL15676575 | 1.00 | MEN1 (1.00) | MEN1KMT2ACYP3A4KDM4ETP53 | |
| SCHEMBL29437764 | 1.00 | MEN1 (1.00) | MEN1KMT2ACYP3A4KDM4ETP53 | |
| SCHEMBL27451564 | 0.98 | MEN1 (0.97) | MEN1KMT2ACYP3A4KDM4ETP53 | |
| Fisetin SCHEMBL4887417 | 0.89 | MEN1 (0.81) | MEN1KMT2ACYP3A4KDM4ETP53 | |
| SCHEMBL3066182 | 0.88 | MEN1 (0.78) | MEN1KMT2ACYP3A4KDM4ETP53 | |
| SCHEMBL2746872 | 0.87 | MEN1 (0.90) | MEN1KMT2ACYP3A4KDM4ETP53 | |
| SCHEMBL14691035 | 0.87 | MEN1 (0.77) | MEN1KMT2ACYP3A4KDM4ETP53 | |
| SCHEMBL14690781 | 0.87 | MEN1 (0.77) | MEN1KMT2ACYP3A4KDM4ETP53 | |
| Quercetin SCHEMBL111510 | 0.86 | MEN1 (0.76) | MEN1KMT2ACYP3A4KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669625-A | 2-substituted benzopyran-4-one compounds and application thereof | 中国人民解放军第二军医大学 | 2016-06-15 | — | — | CN | claimed |
| US-7897637-B2 | Methods of using flavonoids to enhance memory | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2011-03-01 | — | — | US | claimed |
| WO-2009018326-A2 | SOLUBLE PYRONE ANALOGS METHODS AND COMPOSITIONS | LIMERICK BIOPHARMA, INC. (US) | 2009-02-05 | — | — | WO | claimed |
| WO-2008011538-A2 | METHODS OF USING FLAVONOIDS TO ENHANCE MEMORY | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2008-01-24 | — | — | WO | claimed |
| US-20080021096-A1 | METHODS OF USING FLAVONOIDS TO ENHANCE MEMORY | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2008-01-24 | — | — | US | claimed |
| EP-1438423-B1 | ENZYME ACTIVITY INDICATORS | BURTON MICHAEL (GB) | 2007-12-12 | — | — | EP | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| US-20040235081-A1 | Enzyme activity indicators | BURTON MICHAEL (GB) | 2004-11-25 | — | — | US | claimed |
| EP-1438423-A1 | ENZYME ACTIVITY INDICATORS | Burton, Michael (GB) | 2004-07-21 | — | — | EP | claimed |
| EP-1435930-A2 | ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2004-07-14 | — | — | EP | claimed |
| WO-2003035900-A1 | ENZYME ACTIVITY INDICATORS | BURTON MICHAEL (GB) | 2003-05-01 | — | — | WO | claimed |
| WO-2003032969-A2 | ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2003-04-24 | — | — | WO | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| EP-1109800-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LIMITED (KR) | 2001-06-27 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| WO-2000012496-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LTD. (KR) | 2000-03-09 | — | — | WO | claimed |
| EP-0290442-A4 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. | CHEMEX PHARMACEUTICALS INC (US) | 1990-07-03 | — | — | EP | claimed |
| EP-0290442-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-11-17 | — | — | EP | claimed |
| WO-1988003805-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-06-02 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021096-A1 | METHODS OF USING FLAVONOIDS TO ENHANCE MEMORY | FOS, CREBBP, CREB1 | MEN1 3520/4885KMT2A 1152/4885CYP3A4 4468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.