Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.74 |
| ▸ | MAPT | P10636 | 10/20 | 0.74 |
| ▸ | TP53 | P04637 | 8/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.74 |
| ▸ | HPGD | P15428 | 8/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.74 |
| ▸ | CASP1 | P29466 | 5/20 | 0.74 |
| ▸ | CASP7 | P55210 | 5/20 | 0.74 |
| ▸ | RECQL | P46063 | 5/20 | 0.74 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.74 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23791700 | 0.90 | MEN1 (0.59) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL13076536 | 0.86 | MEN1 (0.73) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| Fisetin SCHEMBL29394036 | 0.85 | MEN1 (1.00) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| Fisetin SCHEMBL39454 | 0.85 | MEN1 (1.00) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| Fisetin SCHEMBL116861 | 0.85 | MEN1 (1.00) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| Fisetin SCHEMBL29381611 | 0.85 | MEN1 (1.00) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| Fisetin SCHEMBL29349742 | 0.85 | MEN1 (1.00) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| Fisetin SCHEMBL4263659 | 0.84 | CDK5 (1.00) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| Robinetin SCHEMBL217743 | 0.82 | MEN1 (1.00) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| Robinetin SCHEMBL29883566 | 0.82 | MEN1 (1.00) | MEN1KMT2ACYP3A4HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321371-A1 | NOVEL METHODS FOR RAPID DRUG SUSCEPTIBILITY TESTING AND DRUG SCREENS FOR GROWING AND NON-GROWING CELLS OF PROKARYOTIC AND EUKARYOTIC ORIGIN | Zhang, Ying (US) | 2018-05-16 | — | — | EP | disclosed |