Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 11/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13077519 | 0.91 | ADRB2 (0.43) | CYP2D6ADRB2ADRB1PSMB5HTR2A | |
| SCHEMBL13077487 | 0.87 | ADRB2 (0.47) | NPY1RNPY2RPMP22NPSR1TDP1 | |
| SCHEMBL13040113 | 0.87 | NPY1R (0.36) | NPY1RNPY2RPMP22NPSR1TDP1 | |
| SCHEMBL13077708 | 0.86 | ADRB2 (0.43) | ADRB2ADRB1PSMB5ADRB3 | |
| SCHEMBL13077529 | 0.84 | NPY1R (0.39) | NPY1RNPY2RPMP22NPSR1TDP1 | |
| SCHEMBL14571130 | 0.84 | PSMB5 (0.37) | NPY1RNPY2RPMP22NPSR1TDP1 | |
| SCHEMBL13077525 | 0.83 | ADRB1 (0.53) | NPY1RNPY2RPMP22NPSR1TDP1 | |
| SCHEMBL13077539 | 0.79 | ADRB2 (0.53) | NPY1RNPY2RPMP22NPSR1TDP1 | |
| SCHEMBL13040064 | 0.78 | ADRB2 (0.41) | CYP2D6ADRB2ADRB1PSMB5HTR2A | |
| SCHEMBL13077344 | 0.76 | TSHR (0.40) | PMP22TDP1CYP2D6ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825263-B2 | Nitrooxyderivatives of carvedilol and other beta blockers as antihypertensive | NICOX S.A. (FR) | 2010-11-02 | — | — | US | disclosed |