Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25446902 | 0.81 | — | — | |
| SCHEMBL16640725 | 0.73 | THRB (0.36) | — | |
| SCHEMBL12934029 | 0.67 | — | — | |
| SCHEMBL12092812 | 0.67 | — | — | |
| SCHEMBL12092809 | 0.67 | — | — | |
| SCHEMBL12092811 | 0.67 | — | — | |
| SCHEMBL18622092 | 0.67 | — | — | |
| SCHEMBL11892456 | 0.67 | — | — | |
| SCHEMBL19263924 | 0.67 | — | — | |
| SCHEMBL18530020 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037355-B2 | Triterpene saponin analogues | ADJUVANCE TECHNOLOGIES, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20230357302-A1 | TRITERPENE SAPONIN VARIANTS, METHODS OF SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2023-11-09 | — | — | US | disclosed |
| US-20230263886-A1 | VACCINES, VACCINE PRIMING, AND ANTIGEN DOSE SPARING | ADJUVANCE TECHNOLOGIES, INC. | 2023-08-24 | — | — | US | disclosed |
| US-20230219991-A1 | TRITERPENE SAPONIN ANALOGUES | ADJUVANCE TECHNOLOGIES, INC. (US) | 2023-07-13 | — | — | US | disclosed |
| US-20230131867-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | SLOAN KETTERING INST CANCER RES (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230128815-A1 | ADJUVANT COMPOUNDS, SALT FORMS, AND FORMULATIONS | ADJUVANCE TECH INC (US) | 2023-04-27 | — | — | US | disclosed |
| US-20170283450-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | MEMORIAL SLOAN-KETTERING INST FOR CANCER RES (US) | 2017-10-05 | — | — | US | disclosed |
| US-9718850-B2 | Triterpene saponins, methods of synthesis and uses thereof | MEMORIAL SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-08-01 | — | — | US | disclosed |
| US-20150086585-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | MEMORIAL SLOAN KETTERING INST FOR CANCER RES (US) | 2015-03-26 | — | — | US | disclosed |
| US-8889842-B2 | Triterpene saponins, methods of synthesis, and uses thereof | Sloan-Kettering Insititute for Cancer Research (US) | 2014-11-18 | — | — | US | disclosed |
| US-20130011421-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2013-01-10 | — | — | US | disclosed |
| US-8283456-B2 | Triterpene saponins, methods of synthesis, and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2012-10-09 | — | — | US | disclosed |
| US-20110300177-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130011421-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF | LSS, CYP51A1, TLR7 | ALDH1A1 4567/4885 |
| US-20230219991-A1 | TRITERPENE SAPONIN ANALOGUES | LSS, NFATC1, PGGT1B | ALDH1A1 4821/4885 |
| US-20230128815-A1 | ADJUVANT COMPOUNDS, SALT FORMS, AND FORMULATIONS | MYD88, TLR7, NFATC1 | ALDH1A1 4767/4885 |
| US-20230131867-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | LSS, CYP51A1, TLR7 | ALDH1A1 4604/4885 |
| US-20110300177-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF | LSS, CYP51A1, TLR7 | ALDH1A1 4567/4885 |
| US-20230357302-A1 | TRITERPENE SAPONIN VARIANTS, METHODS OF SYNTHESIS AND USE THEREOF | LSS, GALE, CYP4A11 | ALDH1A1 4420/4885 |
| US-20150086585-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | LSS, CYP51A1, TLR7 | ALDH1A1 4604/4885 |
| US-20230263886-A1 | VACCINES, VACCINE PRIMING, AND ANTIGEN DOSE SPARING | MYD88, CD14, DDOST | ALDH1A1 4863/4885 |
| US-12037355-B2 | Triterpene saponin analogues | LSS, NFATC1, PGGT1B | ALDH1A1 4821/4885 |
| US-20170283450-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | LSS, CYP51A1, TLR7 | ALDH1A1 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.