SCHEMBL13081072

SCHEMBL13081072

O=C1O[C@@H](CO)CN1c1ccc(-n2cnc(CO)c2)c(F)c1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CALML3 P27482 7/20 0.56
MAOA P21397 8/20 0.49
MAOB P27338 8/20 0.47
CYP2C19 P33261 2/20 0.47
CYP2C9 P11712 1/20 0.47
CYP3A4 P08684 1/20 0.46
LMNA P02545 1/20 0.46
PTGS1 P23219 1/20 0.46
SDHA P31040 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8822067 0.90 CALML3 (0.56) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL5235589 0.88 CALML3 (0.56) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL5834576 0.88 CALML3 (0.56) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL14024091 0.87 CALML3 (0.43) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL3755880 0.87 MAOA (0.65) CALML3MAOAMAOBLMNAPTGS1
SCHEMBL3754635 0.87 MAOA (0.65) CALML3MAOAMAOBLMNAPTGS1
SCHEMBL5230449 0.86 MAOA (0.53) CALML3MAOAMAOBCYP3A4
SCHEMBL5833572 0.86 CALML3 (0.48) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL3757473 0.86 CALML3 (0.48) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL13939850 0.86 CALML3 (0.54) CALML3MAOAMAOBCYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100298384-A1 NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS DR. REDDY'S LABORATORIES LTD. (IN) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298384-A1 NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS OXA1L, MIF, VIP CALML3 4408/4885MAOA 3034/4885MAOB 2709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.