Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HSD17B14 | Q9BPX1 | 4/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13083681 | 0.88 | CNR2 (0.40) | CNR2ALDH1A1L3MBTL1LCKMAPK14 | |
| SCHEMBL2420780 | 0.88 | NOTUM (0.37) | CNR2ALDH1A1L3MBTL1NOTUMBRAF | |
| SCHEMBL2420766 | 0.82 | CNR2 (0.35) | CNR2ALDH1A1HSD17B14 | |
| SCHEMBL2412215 | 0.79 | BRAF (0.38) | CNR2ALDH1A1L3MBTL1LCKMAPK14 | |
| SCHEMBL2415707 | 0.76 | HPGD (0.40) | CNR2ALDH1A1 | |
| SCHEMBL12284194 | 0.75 | TAS1R3 (0.40) | CNR2ALDH1A1L3MBTL1HSD17B14 | |
| SCHEMBL2412521 | 0.75 | KIF11 (0.36) | CNR2ALDH1A1L3MBTL1NOTUM | |
| SCHEMBL2412539 | 0.72 | MAPK1 (0.38) | CNR2ALDH1A1L3MBTL1 | |
| SCHEMBL3493689 | 0.72 | NOTUM (0.59) | ALDH1A1L3MBTL1NOTUM | |
| SCHEMBL2416376 | 0.70 | SRD5A2 (0.44) | CNR2ALDH1A1L3MBTL1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508513-A1 | 2-PYRIDONE COMPOUNDS | Taisho Pharmaceutical Co., Ltd. (JP) | 2012-10-10 | — | — | EP | disclosed |