Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 3/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16676214 | 0.79 | TSHR (0.42) | LMNACA2CA12CA1CA9 | |
| SCHEMBL2413125 | 0.79 | HSD11B1 (0.40) | LMNACA2CA12CA1CA9 | |
| SCHEMBL25258150 | 0.79 | CA1 (0.44) | LMNACA2CA1MAPTEPHX2 | |
| SCHEMBL30714245 | 0.75 | CA2 (0.50) | KDM4EGLACA2CA12CA1 | |
| SCHEMBL5307516 | 0.75 | CA2 (0.50) | KDM4EGLACA2CA12CA1 | |
| SCHEMBL20335454 | 0.75 | GAA (0.46) | GLALMNAWDR5 | |
| SCHEMBL13380519 | 0.73 | GAA (0.56) | FEN1ALOX5APLMNACA2CA12 | |
| SCHEMBL31251140 | 0.73 | GAA (0.56) | FEN1ALOX5APLMNACA2CA12 | |
| SCHEMBL17533120 | 0.73 | KDM4E (0.38) | KDM4EGLACA2CA12CA1 | |
| SCHEMBL6937875 | 0.73 | KDM4E (0.42) | KDM4EGLACA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508513-A1 | 2-PYRIDONE COMPOUNDS | Taisho Pharmaceutical Co., Ltd. (JP) | 2012-10-10 | — | — | EP | disclosed |