SCHEMBL1308481

SCHEMBL1308481

COc1cccc(/C=C/C=O)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.62
CCNB2 O95067 3/20 0.59
CDK1 P06493 3/20 0.59
CDK4 P11802 3/20 0.59
CCNB1 P14635 3/20 0.59
CCND1 P24385 3/20 0.59
CCNB3 Q8WWL7 3/20 0.59
NFE2L2 Q16236 3/20 0.59
CYP1A1 P04798 2/20 0.58
CYP1A2 P05177 2/20 0.58
CYP1B1 Q16678 2/20 0.58
FBP1 P09467 1/20 0.58
CYP19A1 P11511 1/20 0.57
NQO2 P16083 1/20 0.57
CHRM2 P08172 1/20 0.56
CHRM1 P11229 1/20 0.56
CHRM3 P20309 1/20 0.56
TUBB4A P04350 1/20 0.56
TUBB P07437 1/20 0.56
TUBA3C P0DPH7 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25259513 1.00 RELA (0.62) RELACCNB2CDK1CDK4CCNB1
SCHEMBL29897304 1.00 RELA (0.62) RELACCNB2CDK1CDK4CCNB1
SCHEMBL1308087 1.00 RELA (0.62) RELACCNB2CDK1CDK4CCNB1
SCHEMBL31317665 0.84 RELA (0.84) RELANFE2L2CYP1A1CYP1A2CYP1B1
SCHEMBL23158820 0.84 RELA (0.84) RELANFE2L2CYP1A1CYP1A2CYP1B1
SCHEMBL700055 0.84 RELA (0.84) RELANFE2L2CYP1A1CYP1A2CYP1B1
SCHEMBL700056 0.84 RELA (0.84) RELANFE2L2CYP1A1CYP1A2CYP1B1
SCHEMBL7592867 0.83 RELA (0.70) RELANFE2L2CYP1A1CYP1A2CYP1B1
Cinnamaldehyde SCHEMBL29125665 0.83 ALDH1A1 (0.69) RELACCNB2CDK1CDK4CCNB1
SCHEMBL7592868 0.83 RELA (0.70) RELANFE2L2CYP1A1CYP1A2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302678-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2025-10-02 US claimed
US-12350136-B2 Absorbent articles including perfume and cyclodextrins THE PROCTER & GAMBLE COMPANY (US) 2025-07-08 US claimed
EP-4464696-A1 CHEMICALLY DEGRADABLE EPOXY COMPOUND, METHOD FOR PREPARING SAME, EPOXY COMPOSITE MATERIAL COMPRISING SAME, AND DECOMPOSITION METHOD THEREOF Konkuk University Industrial Cooperation Corp. (KR) 2024-11-20 EP claimed
CN-118164997-A Sesquiterpene lactone scaberol C thioether derivative, and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164996-A Sesquiterpene lactone scaberol C selenoether derivative, preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164998-A Sesquiterpene lactone scaberol C dithio carbamate derivative and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
US-20230365742-A1 CHEMICALLY DEGRADABLE EPOXY COMPOUND, METHOD OF PREPARING SAME COMPOUND, EPOXY COMPOSITE MATERIAL CONTAINING SAME COMPOUND, AND METHOD OF DEGRADING SAME COMPOSITE MATERIAL KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORP (KR) 2023-11-16 US claimed
US-20220401275-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2022-12-22 US claimed
US-11458049-B2 Absorbent articles including perfume and cyclodextrins THE PROCTER & GAMBLE COMPANY (US) 2022-10-04 US claimed
CN-114272323-A Traditional Chinese medicine formula for regulating and controlling intestinal function of lactating women 华子昂 2022-04-05 CN claimed
CN-109020794-A The preparation method of 3- methoxycinnamic aldehyde 上海华堇生物技术有限责任公司 2018-12-18 CN claimed
WO-2018048852-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS THE PROCTER & GAMBLE COMPANY (US) 2018-03-15 WO claimed
US-20180064588-A1 Absorbent Articles Including Perfume and Cyclodextrins THE PROCTER & GAMBLE COMPANY 2018-03-08 US claimed
CN-102992981-A Industrial preparation method of 3-methoxycinnamaldehyde HUBEI YUANCHENG PHARMACEUTICAL 2013-03-27 CN claimed
US-20100292158-A1 Compositions and Methods for Enhanced Pharmacological Activity of Compositions Comprising Peptide Drug Substances IMMUPHARMA SA (FRANCE) 2010-11-18 US claimed
US-7671029-B2 Compositions and methods for enhanced pharmacological activity of compositions comprising peptide drug substances IMMUPHARMA SA (FR) 2010-03-02 US claimed
US-7321044-B2 Synthesis of oxygen-substituted benzocycloheptenes as valuable intermediate products for the production of tissue-selective estrogens SCHERING AKTIENGESELLSCHAFT (DE) 2008-01-22 US claimed
CN-1602298-A Synthesis of oxygen-substituted benzocycloheptenes, used as valuable intermediate products for producing tissue-selective oestrogens SCHERING AG (DE) 2005-03-30 CN claimed
US-20040186058-A1 Compositions and methods for enhanced pharmacological activity of compositions comprising peptide drug substances UREKA SARL (FR) 2004-09-23 US claimed
US-20030162974-A1 Synthesis of oxygen-substituted benzocycloheptenes as valuable intermediate products for the production of tissue-selective estrogens SCHERING AG (DE) 2003-08-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162974-A1 Synthesis of oxygen-substituted benzocycloheptenes as valuable intermediate products for the production of tissue-selective estrogens CYP19A1, HSD17B11, SULT1E1 RELA 1375/4885CCNB2 670/4885CDK1 339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.