SCHEMBL13085229

SCHEMBL13085229

Cc1cc(C#N)cc(C(=O)NC(C)(C)C)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ncccc1C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 10/20 0.34
SLC2A3 P11169 10/20 0.34
SLC2A4 P14672 10/20 0.34
SLC2A2 P11168 5/20 0.34
GAA P10253 1/20 0.34
MAPK13 O15264 1/20 0.32
MAPK12 P53778 1/20 0.32
MAPK11 Q15759 1/20 0.32
MAPK14 Q16539 1/20 0.32
TRPV1 Q8NER1 2/20 0.32
PPARG P37231 1/20 0.32
CACNA1H O95180 1/20 0.31
P2RX7 Q99572 1/20 0.30
CETP P11597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10075522 0.94 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL29572688 0.93 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL798276 0.93 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL10075521 0.93 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL13084917 0.92 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2MAPK13
SCHEMBL13085207 0.92 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2MAPK13
SCHEMBL13085208 0.92 SLC2A1 (0.39) SLC2A1SLC2A3SLC2A4SLC2A2MAPK13
SCHEMBL13085206 0.90 MAPK14 (0.42) SLC2A1SLC2A3SLC2A4SLC2A2MAPK13
SCHEMBL13084900 0.90 GAA (0.35) GAAMAPK13MAPK12MAPK11MAPK14
SCHEMBL13084905 0.90 GAA (0.35) GAAMAPK13MAPK12MAPK11MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 SLC2A1 2324/4885SLC2A3 2023/4885SLC2A4 2344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.