SCHEMBL798276

SCHEMBL798276

Cc1cc(C#N)cc(C(=O)NC(C)(C)C)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 14/20 0.35
SLC2A3 P11169 14/20 0.35
SLC2A4 P14672 14/20 0.35
SLC2A2 P11168 6/20 0.35
SLC16A3 O15427 1/20 0.33
SLC16A1 P53985 1/20 0.33
MCTS1 Q9ULC4 1/20 0.33
DHODH Q02127 2/20 0.31
CACNA1H O95180 1/20 0.31
ALDH1A1 P00352 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29572688 1.00 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2SLC16A3
SCHEMBL13085487 0.95 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2SLC16A3
SCHEMBL10083628 0.95 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2SLC16A3
SCHEMBL11928376 0.95 SLC16A3 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2SLC16A3
SCHEMBL15488794 0.94 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2SLC16A3
SCHEMBL10075522 0.94 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL13085118 0.94 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2SLC16A3
SCHEMBL13085229 0.93 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL798149 0.93 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL29454974 0.93 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 EP claimed
EP-3395171-A1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2018-10-31 EP claimed
EP-3010889-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-10-03 EP claimed
EP-2793578-B1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-06-06 EP claimed
EP-2925142-B1 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2018-01-31 EP claimed
US-9867377-B2 Composition comprising a biological control agent and an insecticide BAYER CROPSCIENCE AG (DE) 2018-01-16 US claimed
US-20170265479-A1 COMPOSITION COMPRISING BIOLOGICAL CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2017-09-21 US claimed
US-9693565-B2 Composition comprising biological control agents BAYER CROPSCIENCE AG (DE) 2017-07-04 US claimed
US-9642363-B2 N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides BAYER CROPSCIENCE AG (DE) 2017-05-09 US claimed
US-9510596-B2 Binary pesticidal and fungicidal mixtures BAYER CROPSCIENCE AG (DE) 2016-12-06 US claimed
US-20150148230-A1 COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2015-05-28 US claimed
US-20140315898-A1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2014-10-23 US claimed
EP-2790512-A1 ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES Bayer Intellectual Property GmbH (DE) 2014-10-22 EP claimed
WO-2014083031-A2 BINARY PESTICIDAL AND FUNGICIDAL MIXTURES BAYER CROPSCIENCE AG (DE) 2014-06-05 WO claimed
EP-2699092-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND AN INSECTICIDAL OR ACARICIDAL OR NEMATICIDAL ACTIVE COMPOUND Bayer Intellectual Property GmbH (DE) 2014-02-26 EP claimed
US-20140051576-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND AN INSECTICIDAL OR ACARICIDAL OR NEMATICIDAL ACTIVE COMPOUND BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2014-02-20 US claimed
EP-2606726-A1 N-Arylamidine-substituted trifluoroethylsulfide derivatives as acaricides and insecticides Bayer CropScience AG (DE) 2013-06-26 EP claimed
WO-2013087709-A1 ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-06-20 WO claimed
EP-2604118-A1 Active ingredient combinations having insecticidal and acaricidal properties Bayer CropScience AG (DE) 2013-06-19 EP claimed
WO-2012143125-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND AN INSECTICIDAL OR ACARICIDAL OR NEMATICIDAL ACTIVE COMPOUND BAYER CROPSCIENCE AG (DE) 2012-10-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140315898-A1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES AFF4, ARSA, AFF1 SLC2A1 4208/4885SLC2A3 3515/4885SLC2A4 3206/4885
US-20150148230-A1 COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE DDT, ACHE, BROX SLC2A1 4884/4885SLC2A3 4879/4885SLC2A4 4882/4885
US-20140051576-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND AN INSECTICIDAL OR ACARICIDAL OR NEMATICIDAL ACTIVE COMPOUND AADAC, TUBA3C, ACACA SLC2A1 4829/4885SLC2A3 4762/4885SLC2A4 4786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.