SCHEMBL13085482

SCHEMBL13085482

CNC(=O)c1cc(Cl)cc(Cl)c1NC(=O)c1cc(Cn2nnnc2C(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.31
EPHX2 P34913 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MALT1 Q9UDY8 1/20 0.31
NTRK1 P04629 4/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085508 0.94 DHODH (0.33) DHODHALDH1A1MALT1
SCHEMBL13085593 0.93 DHODH (0.32) DHODHALDH1A1
SCHEMBL13085410 0.92 DHODH (0.30) DHODH
SCHEMBL13085242 0.90 MAPK8 (0.36) NTRK1
SCHEMBL12293508 0.89 DHODH (0.32) DHODH
SCHEMBL13085241 0.89 IDO1 (0.34)
SCHEMBL13085032 0.88 NTRK1 (0.34) DHODHEPHX2ALDH1A1MALT1NTRK1
SCHEMBL13085533 0.87 SLC2A1 (0.33) DHODH
SCHEMBL13085238 0.87 DHODH (0.32) DHODHMALT1
SCHEMBL13085506 0.87 NTRK1 (0.32) DHODHEPHX2ALDH1A1MALT1NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 DHODH 2604/4885EPHX2 3688/4885ALDH1A1 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.