SCHEMBL13085508

SCHEMBL13085508

CNC(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(Cn2nnnc2C(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.33
BRD4 O60885 2/20 0.31
BRD3 Q15059 2/20 0.31
MALT1 Q9UDY8 2/20 0.31
CREBBP Q92793 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085482 0.94 DHODH (0.31) DHODHMALT1ALDH1A1
SCHEMBL13085238 0.93 DHODH (0.32) DHODHMALT1
SCHEMBL13085542 0.92 DHODH (0.32) DHODH
SCHEMBL13085533 0.92 SLC2A1 (0.33) DHODH
SCHEMBL13085521 0.91 CRHR1 (0.36) MALT1ALDH1A1
SCHEMBL13085520 0.89 IDO1 (0.33) DHODHMALT1
SCHEMBL12242820 0.89 DHODH (0.31) DHODH
SCHEMBL684736 0.89 NTRK1 (0.33) DHODHMALT1ALDH1A1
SCHEMBL687025 0.87 DHODH (0.32) DHODHMALT1
SCHEMBL13085593 0.87 DHODH (0.32) DHODHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 DHODH 2604/4885BRD4 3218/4885BRD3 3031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.