SCHEMBL13085512

SCHEMBL13085512

Cc1cc(Cl)cc(C(=O)NC(C)(C)C)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ccccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
HPGD P15428 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CNR2 P34972 3/20 0.33
CNR1 P21554 2/20 0.33
F2 P00734 2/20 0.32
F10 P00742 2/20 0.32
PTGER1 P34995 1/20 0.32
SLC16A3 O15427 6/20 0.32
SLC16A1 P53985 5/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
IDH1 O75874 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085424 0.94 NPC1 (0.34) NPC1RAB9AHPGDL3MBTL1MEN1
SCHEMBL13085000 0.93 F10 (0.32) NPC1RAB9AHPGDL3MBTL1MEN1
SCHEMBL13090573 0.93 CNR2 (0.34) NPC1RAB9AMEN1KMT2ACNR2
SCHEMBL10151093 0.92 NPC1 (0.35) NPC1RAB9AHPGDL3MBTL1MEN1
SCHEMBL13090577 0.92 NPC1 (0.33) NPC1RAB9AHPGDL3MBTL1SMN1; SMN2
SCHEMBL13085454 0.91 KMT2A (0.36) MEN1KMT2AF10
SCHEMBL10076311 0.91 SLC2A1 (0.35) MEN1KMT2ACNR1SLC16A3SLC16A1
SCHEMBL684754 0.91 MEN1 (0.32) NPC1RAB9AHPGDL3MBTL1MEN1
SCHEMBL13085480 0.91 CNR2 (0.33) NPC1RAB9AMEN1KMT2ACNR2
SCHEMBL685544 0.89 DHODH (0.33) NPC1RAB9AHPGDL3MBTL1SLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2484676-B1 Tetrazol-substituted anthranilic acid amides as pesticides BAYER CROPSCIENCE AG (DE) 2015-01-21 EP disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 NPC1 4044/4885RAB9A 1451/4885HPGD 4664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.