Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310529 | 0.88 | RORC (0.51) | F2RL3ALDH1A1CYP1A2 | |
| SCHEMBL1310632 | 0.83 | KMT2A (0.50) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL1308405 | 0.82 | PDE5A (0.46) | F2RL3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1308781 | 0.81 | ALDH1A1 (0.43) | F2RL3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL30928910 | 0.76 | MEN1 (0.56) | F2RL3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1308409 | 0.74 | PDE5A (0.46) | MEN1KMT2AALDH1A1HPGDRAB9A | |
| SCHEMBL4483857 | 0.74 | F2RL3 (0.67) | F2RL3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7367052 | 0.72 | F2RL3 (0.53) | F2RL3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7367645 | 0.72 | F2RL3 (0.55) | F2RL3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL363569 | 0.71 | F2RL3 (1.00) | F2RL3KMT2AALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053459-B1 | Selenolopyrazole derivatives and use thereof as anticancer agents | CHINA MEDICAL UNIVERSITY (TW) | 2011-11-08 | — | — | US | disclosed |