Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2777155 | 0.84 | KCNJ1 (0.44) | RAB9AKDM4ESMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL221039 | 0.80 | KCNJ1 (0.54) | KDM4ESMN1; SMN2ALDH1A1CYP2C9LMNA | |
| Hydrochloric Acid SCHEMBL4902833 | 0.79 | KCNJ1 (0.53) | KDM4ESMN1; SMN2ALDH1A1CYP2C9LMNA | |
| SCHEMBL13086302 | 0.78 | ALDH1A1 (0.42) | RAB9AKDM4ESMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL2777577 | 0.77 | ALDH1A1 (0.48) | RAB9ASMN1; SMN2ALDH1A1CYP2C9ALOX15 | |
| SCHEMBL15754004 | 0.76 | KCNJ1 (0.44) | RAB9AKDM4ESMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL30362252 | 0.76 | KCNJ1 (0.44) | RAB9AKDM4ESMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL2779362 | 0.75 | RAB9A (0.48) | RAB9AKDM4ESMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL13086654 | 0.75 | KCNJ1 (0.44) | RAB9AKDM4ESMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL15754634 | 0.74 | HSD17B10 (0.53) | KDM4ESMN1; SMN2ALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118968-A1 | NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-10-21 | — | — | WO | disclosed |