⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20393411 | 0.81 | NPC1 (0.32) | — | |
| SCHEMBL31728102 | 0.75 | P2RX3 (0.32) | — | |
| SCHEMBL9833178 | 0.74 | — | — | |
| SCHEMBL12091358 | 0.70 | NPC1 (0.42) | — | |
| SCHEMBL13934564 | 0.70 | PDE10A (0.41) | — | |
| SCHEMBL798496 | 0.69 | AHR (0.35) | — | |
| Hydrochloric Acid SCHEMBL31728514 | 0.69 | PDE10A (0.40) | — | |
| SCHEMBL9833410 | 0.69 | RAB9A (0.60) | — | |
| SCHEMBL22800215 | 0.68 | AHR (0.32) | — | |
| SCHEMBL13086589 | 0.67 | KDM5B (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| US-20100261679-A1 | CSF-1R, Inhibitors, Compositions, and Methods of Use | NOVARTIS AG (CH) | 2010-10-14 | — | — | US | disclosed |