Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13085765 | 0.90 | MEN1 (0.39) | ALDH1A1SMN1; SMN2SRCMEN1KMT2A | |
| SCHEMBL13086390 | 0.90 | HDAC3 (0.30) | — | |
| SCHEMBL2781567 | 0.89 | MAPT (0.33) | CYP2C9ALDH1A1SMN1; SMN2CYP1A2HSP90AA1 | |
| SCHEMBL2779232 | 0.87 | KDM4E (0.33) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL13086598 | 0.82 | MEN1 (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL13085814 | 0.80 | EPHX2 (0.39) | CYP2C9ALDH1A1SMN1; SMN2CYP1A2HSP90AA1 | |
| SCHEMBL13086318 | 0.80 | ALDH1A1 (0.40) | CYP2C9ALDH1A1SMN1; SMN2CYP1A2HSP90AA1 | |
| SCHEMBL13086335 | 0.74 | ALDH1A1 (0.42) | CYP2C9ALDH1A1SMN1; SMN2CYP1A2HSP90AA1 | |
| SCHEMBL13086356 | 0.72 | ALDH1A1 (0.41) | CYP2C9ALDH1A1SMN1; SMN2CYP1A2HSP90AA1 | |
| SCHEMBL13086368 | 0.72 | ALDH1A1 (0.41) | CYP2C9ALDH1A1SMN1; SMN2CYP1A2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118968-A1 | NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-10-21 | — | — | WO | disclosed |