Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781567 | 0.87 | MAPT (0.33) | ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL13086347 | 0.87 | CYP2C9 (0.32) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13086390 | 0.85 | HDAC3 (0.30) | — | |
| SCHEMBL13085765 | 0.76 | MEN1 (0.39) | ALDH1A1TRPA1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13086343 | 0.70 | CTSK (0.38) | TRPA1TSHRMEN1KMT2A | |
| SCHEMBL13086598 | 0.68 | MEN1 (0.38) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2778319 | 0.67 | ALDH1A1 (0.42) | KDM4EPOLBALDH1A1GLAGAA | |
| SCHEMBL13085814 | 0.66 | EPHX2 (0.39) | KDM4EPOLBALDH1A1GLAGAA | |
| SCHEMBL2778886 | 0.65 | ALDH1A1 (0.42) | KDM4EPOLBALDH1A1GLAGAA | |
| SCHEMBL13086318 | 0.64 | ALDH1A1 (0.40) | KDM4EPOLBALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118968-A1 | NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010118968-A1 | NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-10-21 | — | — | WO | disclosed |