Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 13/20 | 0.58 |
| ▸ | PARP1 | P09874 | 8/20 | 0.58 |
| ▸ | F7 | P08709 | 1/20 | 0.58 |
| ▸ | F3 | P13726 | 1/20 | 0.58 |
| ▸ | PARP11 | Q9NR21 | 9/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562600 | 0.87 | PARP10 (0.58) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL23757293 | 0.83 | CLK4 (0.51) | PARP10PARP1F7F3GRM5 | |
| SCHEMBL246168 | 0.77 | PARP10 (0.69) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL29438680 | 0.77 | PARP10 (0.69) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL14984344 | 0.77 | PARP10 (0.58) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL30947279 | 0.76 | PARP10 (0.58) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL29267558 | 0.76 | PARP10 (0.58) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL28586692 | 0.75 | PBRM1 (0.58) | — | |
| SCHEMBL29953543 | 0.75 | DRD2 (0.44) | PARP10PARP1F7F3 | |
| SCHEMBL200682 | 0.75 | DRD2 (0.44) | PARP10PARP1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802064-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2014-08-12 | — | — | US | disclosed |
| US-8546564-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| WO-2010118155-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |