Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200682 | 1.00 | DRD2 (0.44) | DRD2DRD4GFERSMN1; SMN2ENPP2 | |
| SCHEMBL5757595 | 0.89 | MAPT (0.42) | DRD2DRD4GFERENPP2CA1 | |
| SCHEMBL203219 | 0.85 | DRD2 (0.58) | DRD2DRD4ENPP2CA1CA2 | |
| SCHEMBL13086372 | 0.75 | PARP10 (0.58) | PARP1PARP10F7F3 | |
| SCHEMBL4608563 | 0.74 | MAPT (0.54) | DRD2DRD4ENPP2CA1CA2 | |
| SCHEMBL29378459 | 0.74 | DRD2 (0.70) | DRD2DRD4GFERSMN1; SMN2PARP1 | |
| SCHEMBL33917 | 0.74 | DRD2 (0.70) | DRD2DRD4GFERSMN1; SMN2PARP1 | |
| SCHEMBL18094182 | 0.73 | CA9 (0.57) | SMN1; SMN2ALDH1A1MAPTCRBN | |
| Hydrochloric Acid SCHEMBL6844316 | 0.72 | DRD2 (0.68) | DRD2DRD4GFERSMN1; SMN2PARP1 | |
| SCHEMBL15329663 | 0.72 | ASIC3 (0.55) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |