Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 13/20 | 0.49 |
| ▸ | TUBB | P07437 | 13/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 13/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 13/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 13/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 13/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 13/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 13/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 13/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 13/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 13/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 13/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 13/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 13/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 13/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307656 | 0.85 | TUBB4A (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1307118 | 0.83 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1307257 | 0.80 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1307483 | 0.79 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1306895 | 0.79 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13632095 | 0.79 | TUBB4A (0.45) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12113469 | 0.78 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1308407 | 0.78 | TUBB4A (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12113432 | 0.78 | TUBB4A (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13632126 | 0.77 | TUBB4A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053439-B2 | Benzophenone derivatives useful for inhibiting formation of microtubule | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2011-11-08 | — | — | US | claimed |
| US-20090275575-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2009-11-05 | — | — | US | claimed |
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | claimed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | claimed |
| EP-2066632-B1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARM CORP (KR) | 2013-09-04 | — | — | EP | disclosed |
| US-8053439-B2 | Benzophenone derivatives useful for inhibiting formation of microtubule | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2011-11-08 | — | — | US | disclosed |
| US-8053439-B2 | Benzophenone derivatives useful for inhibiting formation of microtubule | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2011-11-08 | — | — | US | disclosed |
| US-8053439-B2 | Benzophenone derivatives useful for inhibiting formation of microtubule | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2011-11-08 | — | — | US | disclosed |
| US-20090275575-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275575-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | TUBB1, TUBA1C, TUBB6 | TUBB4A 7/4885TUBB 5/4885TUBA3C 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.