Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.40 |
| ▸ | ATIC | P31939 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13086174 | 0.86 | ENPP2 (0.53) | ENPP2PARP1CHEK1CA1CA2 | |
| SCHEMBL31139487 | 0.76 | CA2 (0.58) | ENPP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL29379996 | 0.76 | PARP1 (0.53) | PARP1CHEK1ROCK2ATICGRM5 | |
| SCHEMBL1536457 | 0.76 | CHEK1 (0.77) | PARP1CHEK1ROCK2ALDH1A1 | |
| SCHEMBL1038250 | 0.76 | PARP1 (0.53) | PARP1CHEK1ROCK2ATICGRM5 | |
| SCHEMBL31352392 | 0.76 | CHEK1 (0.77) | PARP1CHEK1ROCK2ALDH1A1 | |
| SCHEMBL14847334 | 0.73 | PLG (0.53) | ENPP2PARP1ROCK2GRM5KDM4E | |
| SCHEMBL6091 | 0.73 | ENPP2 (1.00) | ENPP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL29419532 | 0.73 | ENPP2 (1.00) | ENPP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL15962132 | 0.73 | MAPK14 (0.46) | ENPP2PARP1ROCK2GRM5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-8802064-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2014-08-12 | — | — | US | disclosed |
| US-8546564-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| WO-2010118155-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |