Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986425 | 0.87 | TBXAS1 (0.39) | TBXAS1ALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL3321495 | 0.80 | TBXAS1 (0.36) | TBXAS1ALDH1A1MAPTEGLN3FAAH | |
| SCHEMBL19441143 | 0.79 | — | — | |
| SCHEMBL27404668 | 0.77 | HSD17B10 (0.37) | TBXAS1ALDH1A1MAPTTDP1CYP19A1 | |
| SCHEMBL29187444 | 0.77 | ALDH1A1 (0.36) | TBXAS1ALDH1A1MAPTEGLN3FAAH | |
| SCHEMBL17447441 | 0.76 | — | — | |
| SCHEMBL29014452 | 0.76 | TBXAS1 (0.36) | TBXAS1ALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL28797381 | 0.76 | TBXAS1 (0.34) | TBXAS1ALDH1A1FAAHMGLLHTT | |
| SCHEMBL17696772 | 0.75 | TBXAS1 (0.42) | TBXAS1MAPTHTR2AHTR2CHTR2B | |
| SCHEMBL17696849 | 0.75 | TBXAS1 (0.42) | TBXAS1MAPTHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117796-A2 | PROCESSES FOR THE PREPARATION OF ALPHA-CHLOROKETONES FROM CARBOXYLIC ACIDS | CODEXIS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |