Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823484 | 0.87 | MAPT (0.53) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL6643103 | 0.85 | TDP1 (0.56) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL2826209 | 0.74 | TDP1 (0.64) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL2826211 | 0.73 | MEN1 (0.46) | MAPTKMT2AMEN1CYP2C19GPR119 | |
| SCHEMBL1925386 | 0.71 | SMN1; SMN2 (0.47) | ALDH1A1KMT2ACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL11560883 | 0.70 | CA1 (0.55) | MAPTSMN1; SMN2 | |
| SCHEMBL29060789 | 0.69 | MAPT (0.73) | MAPTALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL11160156 | 0.68 | TDP1 (0.76) | ALDH1A1KMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL18711334 | 0.68 | ALDH1A1 (0.75) | MAPTALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL8054565 | 0.68 | POLB (0.47) | MAPTALDH1A1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1849469-B1 | Arylsulfonamide derivatives for use as CCR3 antagonists in the treatment of inflammatory and immunological disorders | AXIKIN PHARMACEUTICALS INC (US) | 2010-10-27 | — | — | EP | disclosed |