Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 3/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 14/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217587 | 0.85 | ALOX12 (1.00) | ALOX12ALOX15CYP19A1 | |
| SCHEMBL572236 | 0.85 | ALOX12 (1.00) | ALOX12ALOX15CYP19A1 | |
| SCHEMBL131543 | 0.83 | ALOX12 (0.75) | ALOX12ALOX15CYP19A1 | |
| SCHEMBL16152440 | 0.83 | ALOX12 (0.75) | ALOX12ALOX15CYP19A1 | |
| SCHEMBL5797926 | 0.83 | ALOX12 (0.75) | ALOX12ALOX15CYP19A1 | |
| SCHEMBL13904825 | 0.82 | ALOX12 (0.57) | ALOX12ALOX15CYP19A1MEN1KMT2A | |
| SCHEMBL678222 | 0.80 | ALOX12 (0.79) | ALOX12ALOX15CYP19A1 | |
| SCHEMBL133012 | 0.80 | ALOX12 (0.79) | ALOX12ALOX15CYP19A1 | |
| SCHEMBL4806201 | 0.79 | CYP19A1 (0.77) | ALOX12CYP19A1 | |
| SCHEMBL30951649 | 0.77 | ALOX12 (0.73) | ALOX12ALOX15CYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273891-A1 | ISOFLAVONE METABOLITES | Ruane, Michael (AU) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273891-A1 | ISOFLAVONE METABOLITES | CYP19A1, ESR1, CYP21A2 | ALOX12 2643/4885ALOX15 2835/4885CYP19A1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.