SCHEMBL13090596

SCHEMBL13090596

C=C(C)NC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 7/20 0.34
▸ SLC2A3 P11169 7/20 0.34
▸ SLC2A4 P14672 7/20 0.34
▸ SLC2A2 P11168 3/20 0.34
▸ RIPK1 Q13546 2/20 0.34
▸ KMT2A Q03164 4/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KLKB1 P03952 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ MAPT P10636 1/20 0.33
▸ NTRK1 P04629 1/20 0.32
▸ MAPK14 Q16539 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085168 0.91 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2RIPK1
SCHEMBL13090837 0.90 SLC2A1 (0.32) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085489 0.90 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2RIPK1
SCHEMBL13090544 0.89 KMT2A (0.35) RIPK1KMT2AMEN1KLKB1TSHR
SCHEMBL13090582 0.85 SLC2A1 (0.32) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL13085566 0.83 AR (0.32) SLC2A1SLC2A3SLC2A4SLC2A2MAPT
SCHEMBL13085456 0.82 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL16405131 0.82 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL10083881 0.82 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL13085327 0.82 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 — — US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 SLC2A1 2324/4885SLC2A3 2023/4885SLC2A4 2344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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