SCHEMBL13085566

SCHEMBL13085566

Cc1cc(C#N)cc(C(=O)NC(C)(C)C)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ccc(Cl)cc1

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 2/20 0.32
▸ RXRA P19793 2/20 0.32
▸ RXRB P28702 2/20 0.32
▸ RXRG P48443 2/20 0.32
▸ SLC2A1 P11166 9/20 0.32
▸ SLC2A3 P11169 9/20 0.32
▸ SLC2A4 P14672 9/20 0.32
▸ SLC2A2 P11168 4/20 0.31
▸ CACNA1H O95180 1/20 0.31
▸ CCR1 P32246 1/20 0.31
▸ DHODH Q02127 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ MALT1 Q9UDY8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085489 0.93 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2MAPT
SCHEMBL11928424 0.89 RXRA (0.33) RXRARXRBRXRGCCR1DHODH
SCHEMBL10076311 0.89 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL29572688 0.88 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL798276 0.88 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL11928440 0.87 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085454 0.86 KMT2A (0.36) POLBMAPT
SCHEMBL16405122 0.86 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL13084998 0.86 SLC2A1 (0.32) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL13085168 0.85 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2484676-B1 Tetrazol-substituted anthranilic acid amides as pesticides BAYER CROPSCIENCE AG (DE) 2015-01-21 — — EP disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 — — US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 — — US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 — — US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 AR 1364/4885RXRA 615/4885RXRB 1099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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