Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20264395 | 0.79 | POLB (0.45) | MEN1KMT2AMLYCD | |
| SCHEMBL29940563 | 0.79 | POLB (0.45) | MEN1KMT2AMLYCD | |
| Hydrogen Peroxide SCHEMBL11334349 | 0.69 | LDHA (0.42) | LDHALDHBMEN1KMT2APRKCI | |
| SCHEMBL20277899 | 0.69 | POLB (0.42) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10822849 | 0.68 | TAAR1 (0.43) | LDHALDHBMEN1KMT2APRKCI | |
| SCHEMBL14868950 | 0.68 | MLYCD (0.57) | MEN1KMT2AMLYCDALDH1A1SMN1; SMN2 | |
| SCHEMBL13344300 | 0.67 | PRKCI (0.46) | LDHALDHBMEN1KMT2APRKCI | |
| SCHEMBL22066832 | 0.67 | SRC (0.57) | LDHALDHBMEN1KMT2AALDH1A1 | |
| SCHEMBL9629541 | 0.67 | TAAR1 (0.42) | LDHALDHBMEN1KMT2APRKCI | |
| SCHEMBL24260363 | 0.67 | MLYCD (0.33) | MLYCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123139-A1 | ARYLCARBOXAMIDE DERIVATIVE HAVING SULFAMOYL GROUP | 持田製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |