Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.84 |
| ▸ | GAA | P10253 | 8/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.84 |
| ▸ | MAPT | P10636 | 6/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | GLA | P06280 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | HTR3A | P46098 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13091099 | 0.95 | ALDH1A1 (0.84) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL13091072 | 0.89 | ALDH1A1 (0.84) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL13091073 | 0.86 | ALDH1A1 (0.82) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL13091057 | 0.83 | TSHR (0.84) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL8227995 | 0.82 | HTR3A (1.00) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL13091048 | 0.78 | TSHR (0.91) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL13091079 | 0.78 | HTR3A (0.79) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL8227931 | 0.76 | HTR3A (1.00) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL8230914 | 0.76 | HTR3A (1.00) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL8230918 | 0.75 | HTR3A (1.00) | ALDH1A1GAAKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267671-A1 | COMPOSITIONS AND METHODS FOR APOPTOSIS MODULATORS | VM DISCOVERY INC. | 2010-10-21 | — | — | US | disclosed |
| US-20100267671-A1 | COMPOSITIONS AND METHODS FOR APOPTOSIS MODULATORS | VM DISCOVERY INC. | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267671-A1 | COMPOSITIONS AND METHODS FOR APOPTOSIS MODULATORS | BAX, BCL2, BAD | ALDH1A1 3966/4885GAA 1653/4885KDM4E 3186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.