Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616569 | 0.84 | CYP2C9 (0.40) | TP53TDP1KMT2AMEN1CYP2C9 | |
| SCHEMBL13091115 | 0.79 | SMN1; SMN2 (0.40) | TP53TDP1KMT2AMEN1CASR | |
| SCHEMBL16672493 | 0.77 | SMN1; SMN2 (0.49) | KMT2AMEN1KDM4ECYP2C9SMN1; SMN2 | |
| SCHEMBL18242406 | 0.76 | TDP1 (0.42) | TP53TDP1KMT2AMEN1CASR | |
| SCHEMBL3640954 | 0.76 | KMT2A (0.40) | TP53TDP1KMT2AMEN1CASR | |
| SCHEMBL18754039 | 0.75 | GABRA1 (0.42) | TDP1KMT2ACASRKDM4ESMN1; SMN2 | |
| SCHEMBL24766024 | 0.74 | ACHE (0.47) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL12180439 | 0.74 | TDP1 (0.46) | TP53TDP1KMT2AMEN1CASR | |
| SCHEMBL7610097 | 0.74 | TDP1 (0.46) | TP53TDP1KMT2AMEN1CASR | |
| SCHEMBL18546040 | 0.74 | CASR (0.53) | TP53TDP1KMT2AMEN1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123139-A1 | ARYLCARBOXAMIDE DERIVATIVE HAVING SULFAMOYL GROUP | 持田製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |