Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13548827 | 0.77 | CHRNB2 (0.46) | CHRNB2CHRNA4ALDH1A1KDM4EMEN1 | |
| SCHEMBL31028076 | 0.77 | PPARD (0.50) | PPARDPPARASRD5A1MTNR1A | |
| SCHEMBL16499816 | 0.76 | CHRNB2 (0.48) | CHRNB2CHRNA4ALDH1A1KDM4EHSD11B1 | |
| SCHEMBL31511361 | 0.76 | CHRNB2 (0.48) | CHRNB2CHRNA4ALDH1A1KDM4EHSD11B1 | |
| SCHEMBL30809688 | 0.75 | CHRNB2 (0.47) | CHRNB2CHRNA4ALDH1A1KDM4EHSD11B1 | |
| SCHEMBL4047281 | 0.75 | CHRNB2 (0.47) | CHRNB2CHRNA4ALDH1A1KDM4EHSD11B1 | |
| SCHEMBL30585547 | 0.75 | CHRNB2 (0.47) | CHRNB2CHRNA4ALDH1A1KDM4EHSD11B1 | |
| SCHEMBL1271484 | 0.75 | CHRNB2 (0.47) | CHRNB2CHRNA4ALDH1A1KDM4EHSD11B1 | |
| SCHEMBL803471 | 0.75 | CHRNB2 (0.47) | CHRNB2CHRNA4ALDH1A1KDM4EHSD11B1 | |
| SCHEMBL27920404 | 0.75 | CHRNB2 (0.47) | CHRNB2CHRNA4ALDH1A1KDM4EHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123017-A1 | TETRAZOLE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |