Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1271484 | 1.00 | CHRNB2 (0.47) | CHRNB2CHRNA4MAPTKDM4EALDH1A1 | |
| SCHEMBL4047281 | 1.00 | CHRNB2 (0.47) | CHRNB2CHRNA4MAPTKDM4EALDH1A1 | |
| SCHEMBL803471 | 1.00 | CHRNB2 (0.47) | CHRNB2CHRNA4MAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2816177 | 0.98 | CHRNB2 (0.46) | CHRNB2CHRNA4MAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2816176 | 0.98 | CHRNB2 (0.46) | CHRNB2CHRNA4MAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL31186907 | 0.98 | CHRNB2 (0.46) | CHRNB2CHRNA4MAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2818950 | 0.98 | CHRNB2 (0.46) | CHRNB2CHRNA4MAPTKDM4EALDH1A1 | |
| SCHEMBL5956791 | 0.91 | ACHE (0.46) | CHRNB2CHRNA4MAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL355728 | 0.90 | ACHE (0.45) | CHRNB2CHRNA4MAPTKDM4EALDH1A1 | |
| SCHEMBL484305 | 0.88 | ACHE (0.52) | CHRNB2CHRNA4MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573080-A1 | INDANE AND COUMARAN DERIVATIVES AS FAST SKELETAL MUSCLE MYOSIN INHIBITORS | Cytokinetics, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024040190-A1 | INDANE AND COUMARAN DERIVATIVES AS FAST SKELETAL MUSCLE MYOSIN INHIBITORS | CYTOKINETICS, INCORPORATED (US) | 2024-02-22 | — | — | WO | disclosed |