Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12711415 | 0.92 | BDKRB2 (0.47) | BDKRB2CYP3A4 | |
| SCHEMBL12711930 | 0.92 | BDKRB2 (0.46) | BDKRB2CYP3A4 | |
| SCHEMBL12711365 | 0.87 | BDKRB2 (0.62) | BDKRB2 | |
| SCHEMBL12712312 | 0.85 | BDKRB2 (0.53) | BDKRB2CYP3A4 | |
| SCHEMBL13093243 | 0.84 | BDKRB2 (0.38) | BDKRB2 | |
| SCHEMBL12711445 | 0.84 | BDKRB2 (0.41) | BDKRB2CYP3A4 | |
| SCHEMBL12711446 | 0.84 | BDKRB2 (0.51) | BDKRB2CYP3A4 | |
| SCHEMBL12712377 | 0.82 | BDKRB2 (0.55) | BDKRB2 | |
| SCHEMBL13093092 | 0.81 | BDKRB2 (0.61) | BDKRB2CYP3A4 | |
| SCHEMBL12711939 | 0.80 | BDKRB2 (0.62) | BDKRB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144897-B1 | 8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS | JERINI AG (DE) | 2010-10-20 | — | — | EP | disclosed |