Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13093223 | 0.90 | MC4R (0.46) | MC4R | |
| SCHEMBL13093222 | 0.90 | MC4R (0.46) | MC4R | |
| SCHEMBL13093040 | 0.88 | MC4R (0.46) | MC4R | |
| SCHEMBL13093265 | 0.80 | MC4R (0.47) | MC4R | |
| SCHEMBL13093503 | 0.80 | MC4R (0.47) | MC4R | |
| SCHEMBL13093215 | 0.80 | SLC6A3 (0.50) | MC4R | |
| SCHEMBL13093026 | 0.80 | SLC6A3 (0.50) | MC4R | |
| SCHEMBL13093168 | 0.79 | HDAC2 (0.42) | MC4R | |
| SCHEMBL13093041 | 0.79 | HDAC2 (0.42) | MC4R | |
| SCHEMBL13093088 | 0.76 | SLC6A2 (0.41) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123006-A1 | PYRROLIDINE COMPOUND | 武田薬品工業株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |