SCHEMBL13093223 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	9/20	0.46

▸	SLC6A2	P23975	2/20	0.44

▸	SLC6A4	P31645	2/20	0.44

▸	SLC6A3	Q01959	2/20	0.44

▸	TSHR	P16473	1/20	0.44

▸	HPGD	P15428	1/20	0.43

▸	MEN1	O00255	1/20	0.40

▸	NPC1	O15118	1/20	0.40

▸	RAB9A	P51151	1/20	0.40

▸	KMT2A	Q03164	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13093222	1.00	MC4R (0.46)	MC4RSLC6A2SLC6A4SLC6A3TSHR
SCHEMBL13093040	0.97	MC4R (0.46)	MC4RSLC6A2SLC6A4SLC6A3TSHR
SCHEMBL13093032	0.90	MC4R (0.44)	MC4R
SCHEMBL13093026	0.89	SLC6A3 (0.50)	MC4RSLC6A2SLC6A4SLC6A3TSHR
SCHEMBL13093215	0.89	SLC6A3 (0.50)	MC4RSLC6A2SLC6A4SLC6A3TSHR
SCHEMBL13093088	0.85	SLC6A2 (0.41)	MC4RSLC6A2SLC6A4SLC6A3
SCHEMBL13093259	0.85	SLC6A2 (0.41)	MC4RSLC6A2SLC6A4SLC6A3
SCHEMBL13093025	0.85	SLC6A3 (0.43)	MC4RSLC6A2SLC6A4SLC6A3
SCHEMBL13093265	0.82	MC4R (0.47)	MC4R
SCHEMBL13093503	0.82	MC4R (0.47)	MC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010123006-A1	PYRROLIDINE COMPOUND	武田薬品工業株式会社 (JP)	2010-10-28	—	—	WO	disclosed