SCHEMBL1309352

SCHEMBL1309352

O=C(C1CCCCC1)N1CCC1

nearest known ligand 0.86

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.86
TSHR P16473 1/20 0.86
HPGD P15428 2/20 0.77
LMNA P02545 1/20 0.74
HSD11B1 P28845 9/20 0.62
SMN1; SMN2 Q16637 2/20 0.60
HTT P42858 1/20 0.59
HSD11B2 P80365 2/20 0.57
GRM5 P41594 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3703105 0.97 ALDH1A1 (0.81) ALDH1A1TSHRHPGDLMNAHSD11B1
SCHEMBL2386976 0.95 ALDH1A1 (0.86) ALDH1A1TSHRHPGDLMNAHSD11B1
SCHEMBL60471 0.95 ALDH1A1 (0.86) ALDH1A1TSHRHPGDLMNAHSD11B1
SCHEMBL1826063 0.95 ALDH1A1 (0.86) ALDH1A1TSHRHPGDLMNAHSD11B1
SCHEMBL4057588 0.95 ALDH1A1 (0.86) ALDH1A1TSHRHPGDLMNAHSD11B1
SCHEMBL3695372 0.95 ALDH1A1 (0.86) ALDH1A1TSHRHPGDLMNAHSD11B1
SCHEMBL10559542 0.92 ALDH1A1 (1.00) ALDH1A1TSHRHPGDLMNAHSD11B1
SCHEMBL3708786 0.92 ALDH1A1 (0.73) ALDH1A1TSHRHPGDLMNAHSD11B1
SCHEMBL3703489 0.92 ALDH1A1 (0.81) ALDH1A1TSHRHPGDLMNAHSD11B1
SCHEMBL7131881 0.92 ALDH1A1 (1.00) ALDH1A1TSHRHPGDLMNAHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119955091-A Polymer, positive-type negative-type photosensitive resin composition, pattern forming method, cured film forming method, interlayer insulating film, surface protective film, and electronic component 信越化学工业株式会社 2025-05-09 CN disclosed
CN-118210199-A Photosensitive resin composition, cured film pattern, and method for producing same 奇美实业股份有限公司 2024-06-18 CN disclosed
US-20230312605-A1 PYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF TENARX, INC. 2023-10-05 US disclosed
WO-2023064366-A1 PYRROLO[2,1-F][1,2,4]TRIAZINES DERIVATIVES AS INHIBITORS OF DYRK1A BIOSPLICE THERAPEUTICS, INC. (US) 2023-04-20 WO disclosed
CN-115113484-A Positive photosensitive resin composition, positive photosensitive dry film, method for producing the same, and method for forming pattern 信越化学工业株式会社 2022-09-27 CN disclosed
CN-107561863-B Positive photosensitive resin composition and application thereof 奇美实业股份有限公司 2022-09-16 CN disclosed
CN-114253069-A Photosensitive resin composition, pattern forming method, cured film forming method, interlayer insulating film, and surface protective film 信越化学工业株式会社 2022-03-29 CN disclosed
WO-2019116325-A1 TRICYCLIC COMPOUNDS AS VASOPRESSIN V1A RECEPTOR ANTAGONISTS RICHTER GEDEON NYRT. (HU) 2019-06-20 WO disclosed
US-10162260-B2 Photosensitive resin composition, protective film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-12-25 US disclosed
CN-104860924-B Melanocortin-4 receptor modulators prepare their method and its purposes in human medicine and cosmetics 盖尔德马研究及发展公司 2018-10-09 CN disclosed
CN-104860924-A Melanocortin receptor modulators, process for preparing same and use there in human medicine and cosmetics GALDERMA RES & DEV 2015-08-26 CN disclosed
CN-102203082-B Melanocortin receptor modulators, processes for preparing them and their use in human medicine and cosmetics GALDERMA RES & DEV 2015-04-29 CN disclosed
CN-104375381-A Photosensitive polysiloxane composition, film formed by photosensitive polysiloxane composition and device comprising film CHI MEI CORP 2015-02-25 CN disclosed
US-20150050596-A1 PHOTOSENSITIVE POLYSILOXANE COMPOSITION AND USES THEREOF CHI MEI CORPORATION (TW) 2015-02-19 US disclosed
US-8877968-B2 Melanocortin receptor modulators, process for preparing them and use there in human medicine and cosmetics GALDERMA RESEARCH & DEVELOPMENT (FR) 2014-11-04 US disclosed
EP-2352728-B1 MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS GALDERMA RES & DEV (FR) 2014-05-21 EP disclosed
US-20110275657-A1 MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THERE IN HUMAN MEDICINE AND COSMETICS GALDERMA RESEARCH & DEVELOPMENT (FR) 2011-11-10 US disclosed
CN-102203082-A Melanocortin receptor modulators, processes for preparing them and their use in human medicine and cosmetics GALDERMA RES & DEV 2011-09-28 CN disclosed
EP-2352728-A1 MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS Galderma Research & Development (FR) 2011-08-10 EP disclosed
WO-2010052255-A1 MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS GALDERMA RESEARCH & DEVELOPMENT (FR) 2010-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312605-A1 PYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF DYRK1A, DYRK2, DYRK1B ALDH1A1 3166/4885TSHR 1054/4885HPGD 3630/4885
US-20110275657-A1 MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THERE IN HUMAN MEDICINE AND COSMETICS MC1R, MC5R, MC3R ALDH1A1 2022/4885TSHR 30/4885HPGD 921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.